Tuesday 29 January 2019

Advanced Technologies| Global Oncology Market to $241.0 billion in 2023

Researchmoz added Most up-to-date research on "Global Oncology Market to 2023 - Robust Growth Driven by Rising Prevalence and Increased Uptake of Immune Checkpoint Inhibitors" to its huge collection of research reports.

In 2012, there were 32.6 million people living with any type of cancer within five years of diagnosis. These are generally incurable once they progress to the stage where they are unresectable. Chemotherapy compounds are a mainstay treatment for cancers of all types, at various disease stages. In a typical course of therapy for cancer, multiple chemotherapy compounds are administered sequentially in combination regimens, as an adjunct to surgery and radiation therapy. Chemotherapy drugs are cytotoxic to dividing cells, meaning that they act on both healthy and malignant tissues and are fairly toxic. However, they exert more damage on malignant tissue than healthy tissue due to the rapid cell cycle of cancer cells. The key cancer indications of this report are breast, colorectal, lung, and prostate and hematological cancers.

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A number of common etiologic factors have been strongly characterized as raising the risk of developing cancer, including age, chronic inflammation, gender, obesity, tobacco usage and heritable cancer syndromes. The risk of cancer increases greatly in patients over the age of 65. Populations in developed countries are projected to become increasingly aged and show rising obesity incidence, which will drive both cancer prevalence and revenue growth for its treatments.

There has been a shift towards developing targeted therapies, such as mAbs and cell therapies. Targeted therapies, by their nature, have less toxicity associated with their use and as a result can be administered to more cancer patients, who are commonly elderly and have co-morbidities, therefore increasing the overall survival of this group and the number of treatment cycles they may receive. The most commercially successful oncology treatments are mAbs such as MabThera/Rituxan, Avastin and Herceptin.

Scope

    Global revenue for the oncology market is forecast to grow at a Compound Annual Growth Rate (CAGR) of 10.66%, from $118.6 billion in 2016 to $241.0 billion in 2023. Which drugs will achieve blockbuster status and how will the key player companies perform during the forecast period?
    The oncology pipeline is large and fairly diverse and contains 7,773 products. How does the composition of the pipeline compare with that of the existing market? What are the most popular types of molecule type and molecular target in the pipeline?
    What mechanisms of action and molecule types are most common for pipeline products being trialed in the various key indications?
    How will the market shares and CAGRs of the top 20 pharma companies compare within oncology?
    What proportion of the key players’ revenues will be attributable to oncology products?

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Reasons to buy

    Understand the current clinical and commercial landscape by considering disease pathogenesis, diagnosis, prognosis, and the treatment options available at each stage of diagnosis
    Visualize the composition of the oncology market across each indication, in terms of dominant molecule types and targets, highlighting the key commercial assets and players
    Analyze the oncology pipeline and stratify by stage of development, molecule type and molecular target, with a granular breakdown across key indications
    Understand the growth in patient epidemiology and market revenue for the oncology market globally and across the key players and product types
    Stratify the market in terms of the generic and premium product revenue split between oncology products and assess the role of these product types in the treatment of the various cancers
    Identify commercial opportunities in the oncology deals landscape by analyzing trends in licensing and co-development deals

Table of Contents

1 Table of Contents 5
1.1 List of Tables 7
1.2 List of Figures 7

2 Introduction 10
2.1 Therapy Area Introduction 10
2.2 Symptoms 11
2.3 Diagnosis 12
2.4 Etiology and Pathophysiology 13
2.4.1 Etiology 13
2.4.2 Pathophysiology 15
2.5 Co-morbidities and Complications 16
2.6 Epidemiology Patterns - Prevalence, Patient Segmentation, and Diagnostic and Treatment Usage Rates 17
2.6.1 Breast Cancer 17
2.6.2 Colorectal Cancer 18
2.6.3 Lung Cancer 19
2.6.4 Prostate Cancer 20

3 Key Marketed Products 31
3.1 Overview 31
3.2 MabThera/Rituxan (rituximab) 32
3.3 Avastin (bevacizumab) 33
3.4 Herceptin (trastuzumab) 35
3.5 Revlimid (lenalidomide) 37
3.6 Opdivo (nivolumab) 39
3.7 Xtandi (enzalutamide) 41
3.8 Gleevec/Glivec (imatinib mesylate) 42
3.9 Alimta (pemetrexed) 44
3.10 Zytiga (abiraterone acetate) 46
3.11 Conclusion 47

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4 Pipeline Landscape Assessment 49
4.1 Overview 49
4.2 Pipeline Development Landscape 50
4.3 Molecular Targets in the Pipeline 54
4.4 Clinical Trials 58
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